Get The Facts About Sickle Cell

Q1. What is sickle cell trait and who is affected by it?

A1. Sickle cell trait happens when a person inherits a copy of the sickle hemoglobin gene from one parent and a normal hemoglobin gene from the other parent. People with sickle cell trait are carriers of the sickle hemoglobin gene and they can pass it on when they have a child. A person who inherits two copies of the sickle hemoglobin gene—one from each parent—has sickle cell disease (SCD).

About 1 in 13 Blacks in the United States are born with sickle cell trait.

Please see the below example of an inheritance pattern.

For more information, visit NHLB’s website: http://www.nhlbi.nih.gov/health/health-topics/topics/sca.