Chronic Myeloid Leukemia Patients With History Of Malignancies Can Still Have Positive Outcomes With TKI Treatment
Researchers are learning that a history of malignancies for people living with chronic myeloid leukemia (CML) doesn’t mean there’s a bad ending in sight.
A new study published in the online medical journal Cancer shows that those with the malignancy history can have outcomes as great as those without a malignancy past.
“With prolonged survival, questions arise regarding the effects of TKI (tyrosine kinase inhibitors) treatment on prior medical conditions and the effect on such conditions on the management and outcomes of patients with CML,” the study’s authors wrote.
These results are contrary to recent studies, which have shown an increase in prevalence of other malignancies prior to a patient being diagnosed with CML, according to cancernetwork.com.
The study had 630 participants with chronic CML – all but four of them had a prior malignancy status of some kind. About 10 percent of those had a history of malignancies before being diagnosed with CML.