genetic mutations has a markedly increased risk of developing breast and ovarian cancer.
For instance, in the general population, a woman has a 12% chance of developing breast cancer. However, an individual with a BRCA-1 mutation has a 70% chance of developing breast cancer. Other cancers associated with BRCA mutations include fallopian tube and pancreatic cancer.
Are Genetic Tests Available to Detect BRCA mutations?
Yes, there are several types of tests that require a sample of blood or saliva which contains DNA. The samples are sent to a laboratory for analysis which could take several weeks for a result. Your doctor will call you to discuss the results.
Who Should Consider Testing for BRCA Genetic Mutations?
In the general population, genetic mutations in the BRCA genes are rare. Therefore your personal and family history should be evaluated by a doctor in order to determine what genetic tests are needed. Some factors that may prompt the need for genetic testing include breast cancer before the age of 50, bilateral breast cancer, breast and ovarian cancer in the same family, multiple individuals with breast cancer in a family, and male breast cancer.
If My Test is Positive for a Mutation What Do I Do?
If you do receive a positive result your clinician will refer you to receive counseling and explanation of what the