About 1 in 8 American women will develop breast cancer. In addition to breast exams, and mammograms, some women and men with a family history of breast cancer may also need to get a genetic screening. About 5 to 10% of breast cancers are linked to genetic mutations.
There are many inherited genetic mutations that can increase the likelihood of breast cancer. Two of the most well-known genes are breast cancer gene 1 (BRCA-1) and breast cancer gene 2 (BRCA-2). These genes greatly increase the risk of breast and ovarian cancer.
What are BRCA-1 and BRCA-2?
BRCA-1 and BRCA-2 are tumor suppressor genes. These genes produce tumor suppressor proteins that help repair damaged DNA. When these genes are mutated, they may not be able to perform their normal function which can lead to abnormal cell growth.
What Cancers are Linked to Mutations in BRCA-1 & BRCA-2?
The most common cancers strongly associated with these mutations are breast and ovarian cancer. Anyone with these