Chloroquine/Hydroxychloroquine: Is there any basis to the hype with COVID-19?

 

Since my last article discussing experimental treatments for COVID-19, we have results from a clinical trial conducted in China on the effectiveness of Kaletra (published in the prestigious New England Journal of Medicine). Unfortunately, the study didn’t show any benefit from the drugs. This illustrates a crucial point for everyone to understand: wait for the research! Kaletra works against the virus in a test-tube and it seemed to have some benefit in a related coronavirus; it didn’t work against this coronavirus.  It is important that the studies be designed well with clearly defined markers of success, otherwise the results may not be clear or offer the wrong answer to the question.