additional traces of strong drugs in PC-SPES, including an artificial form of estrogen and a pain reliever called indomethacin that may act against tumor cells.
For a time, it looked as though the product might actually live up to its name. Several scientific studies found the combination of herbs — including saw palmetto, panax pseudo-ginseng, and six assorted Chinese herbs — to be an effective treatment for prostate cancer. But even before the product was recalled, there was cause for concern.
Like some already established prostate cancer treatments, PC-SPES cut off supplies of the male hormone testosterone, a major source of fuel for prostate cancer. According to a report in the August 2001 issue of Urology, the concoction can reduce testosterone dramatically. For patients with prostate cancer, this drastic measure has real benefits. As the level of testosterone plummets, the tumor stops growing (at least temporarily) and may even begin to shrink.
Of course, anything that reduces testosterone to that level is bound to cause side effects. Nipple tenderness and swelling in the breasts are very common. About one-third of patients had diarrhea, and another one-third had cramps in the legs or muscles. Blood clots in the legs or lungs were the most serious potential side effect, but they were also very rare.
In summary, the supposed herbal supplement PC-SPES carried all of the punch of a prescription drug — because it actually contained drugs. The supplement ran afoul of authorities only after tests by the California Department of Health Services turned up traces of warfarin, a prescription blood thinner that can raise the risk of serious bleeding. BotanicLab Inc., the company that distributed PC-SPES, voluntarily recalled the product nationwide. The California Department of Health Services urged anyone using PC-SPES to stop taking the product immediately and seek medical advice.
Quercetin
Quercetin is a flavonoid that is found in capers, apples, onions and many vegetables and fruits. Lab studies have found that quercetin helps to block the growth of prostate cancer cells, and at least one small study showed significant improvement in symptoms of chronic prostatitis. More research is needed, however, before it can be recommended.
As noted before, herbal supplements are not meant to be a supplement to a doctor. You should consult with your doctor before taking any of these supplements to ensure it is safe.