Medication Adherence: The Achille’s Heel of U=U

One of the highlights of 2018 that I wrote about last year was the additional research that enforced the important principle that HIV-infected individuals do not infect other individuals when they are suppressed on medication. The rallying cry is “U=U”, that is “Undetectable equals Untransmissible”. If a person is suppressed on HIV medicine, that means the virus is not detectable in their blood (undetectable). A person who is undetectable does not transmit or spread HIV infection to another person. This is fantastic news and therefore, based on this principle, we can control the epidemic and prevent new infections! So, then why hasn’t this happened? All we have to do is make sure everyone who is infected is suppressed and undetectable. So here’s the reality.