Breast cancer is the most common cancer among African-American women. It is also the second leading cause of cancer deaths among African-American women. However, this new surgery could increase the chances of survival in women with advanced breast cancer.
Women with advanced breast cancer who undergo surgery to remove the tumor after chemotherapy or another type of systemic treatment may live longer than those who don’t have surgery, a new study suggests.
The findings challenge a long-held belief that surgery confers little benefit for women with stage 4 breast cancer unless the cancer is causing pain, bleeding or other symptoms. Stage 4 is the point at which the cancer has spread beyond the breast and nearby lymph nodes to other parts of the body.
“As our systemic therapies to treat breast cancer get better and better, we have to always rethink the paradigms that we have lived by, and we may have been very right to say that surgery added very little for these patients a decade ago, but it’s time to rethink that now,” said study author Dr. Daleela Dodge, an associate professor of surgery at Penn State Cancer Institute in Hershey, Pa.
You May Also Like
Dodge’s team analyzed a nationwide database of close to 13,000 women who had stage 4 breast cancer between 2010 and 2015. Women were treated with chemotherapy, hormone therapies and/or immunotherapies with or without surgery.
The database also included information about their hormonal and HER2 cancer status. These factors are known to affect cancer growth. Women who died within six months of diagnosis were excluded to ensure that only treatment-responsive cancers were studied.
Regardless of hormone receptor or HER2 status, women who had surgery to remove the cancer after chemotherapy or another systemic treatment were more likely to be alive five years later than patients who only received systemic treatments. Systemic treatment only is the current standard of care for stage 4 breast cancer, according to the American Cancer Society.
Women whose breast cancers were HER2 positive saw an even greater survival edge when their treatment plan included surgery, the study showed.
You May Also Like
Women who had surgery after their other treatments fared better than those whose surgery came before systemic treatment.
Stage 4 breast cancers account for 6% of newly diagnosed breast cancers, according to the study. The five-year survival rate for breast cancer that has started to spread is much lower than it is for breast cancers that have not spread elsewhere.
“If you look at other cancers, we treat spreading disease very aggressively with surgery,” Dodge said. “In breast cancer, there has been this paradigm that you don’t perform surgery in metastatic patients, but it’s time to rethink this.”
