… by identifying where the binding occurs, we have a framework for what genes are being turned on or off by STAT3. That was the first sign we may have identified something that may be important.”
This gives them a starting point for how to prevent metastasis, meaning a disease that currently has no targeted therapies could soon have some.
“What we found was that therapies that target STAT3 could prevent metastasis in triple negative breast cancer,” McDaniel said.