blood vessels from causing more vision loss. This therapy causes less damage to the retina than laser treatment. Laser surgery, which destroys the leaky blood vessels that damage the macula, works best if the vessels aren’t directly beneath the center of the retina. Studies by the multi-center Macular Photocoagulation Study Group (MPSG) found that about 25 percent of surgery patients in this best-case category suffer severe vision loss within a year, compared with 40 percent of untreated patients. Unfortunately, blood vessels grow back in about half of all treated patients within one year of surgery. If you have vessels centered beneath your retina, laser surgery will inevitably destroy vital tissue while it wipes out the vessels.
In photodynamic therapy, a drug injected into the arm is attracted to the damaged blood vessels in the eye. Next, a light is aimed at the eyes, activating the drug and causing it to destroy the blood vessels. Unlike laser surgery, photodynamic therapy doesn’t harm healthy tissue. The procedure takes about 20 minutes and can be done in your doctor’s office. Since the drug is triggered by light, you’ll need to avoid exposure to sunlight or bright indoor light for five days after treatment. As with laser surgery, the procedure may need to be repeated as more leaky blood vessels develop.
Today’s treatments leave much room for improvement, and researchers across the country are working to answer the call. Within a few years, patients may be able to choose from a variety of new medications, surgeries, or radiation treatments that can stop macular degeneration without damaging the eye.
Several new therapies under development, in fact, may help reduce or eliminate the need for painful injections in the eye. One, IRay Radiotherapy System, uses radiation to shrink AMD lesions, while another, SalutarisMD treatment, uses radiation to combat the disease. Another new technique under development, AdaptDx Dark Adaptometer, was developed by a doctor who noticed that patients who developed AMD first had significant loss of night vision and created a sort of stress test function for the retina. By contrasting night vision to what healthy people see, doctors may be able to detect and treat AMD at much earlier stages.
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Can vitamins or minerals help?
Experts believe that large doses of certain nutrients can protect your eyes from macular degeneration. If you’re at high risk for the disease or already have the dry form, changing your diet and including nutritional supplements may help protect your vision. A study published in the Archives of Ophthalmology suggests that 20 percent of people at high risk for advanced macular degeneration may be able to avoid it for the next five years if they take special high-dose zinc and antioxidant supplements. The National Eye Institute has completed a second stage of the Age-Related Eye Disease Study (AREDS2) that investigated the potential of vitamins and minerals to slow the progression of macular degeneration. It found that supplements with vitamins C and E, zinc, copper, and beta-carotene reduced the risk of AMD by as much as 25 percent.
Other promising nutrients for preventing macular degeneration in the AREDS2 study were lutein and zeaxanthin, carotenoids found in yellow corn and dark green, leafy vegetables. These pigments are also abundant in the eyes, and they seem to help protect the retina from damage. A study by the National Institutes of Health found that people who ate spinach or collard greens five or more times each week were almost 90 percent less likely to develop macular degeneration. In the AREDS2 study, participants with the worst dietary intake of lutein + zeaxanthin were about 25 percent less likely to develop advanced AMD when supplemented with lutein and zeaxanthin. Interestingly, the carotenoids appeared to compete with beta-carotene in terms of absorption, so researchers advise not using beta-carotene supplements at the same time.
Green vegetables are undoubtedly good for you, but it may not be wise to load up on lutein or zeaxanthin supplements. Carotenoids can have unwanted effects in large doses; for instance, too much lutein can block the effects of lycopene, another carotenoid that may help prevent lung cancer and prostate cancer. In general, you’re better off getting your protection in natural forms.