overactivity in the TLR7 pathway. By confirming a causal link between the gene mutation and the disease, we can start to search for more effective treatments,” says study co-author Nan Shen, co-director of CACPI.
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Combatting lupus
African Americans, Hispanics, Latinos, and Asian Americans have a higher risk of developing lupus nephritis than white people.
Researchers are unclear why lupus affects so many Black people, however, they believe it may be linked to:
- genetics
- hormones
- environmental factors
It can be difficult for doctors to diagnose lupus because there is no specific test for the disease and many of the symptoms of lupus may resemble the symptoms of other diseases.
To successfully get a diagnosis, doctors will use a combination of laboratory tests and symptom assessments.
There is also a set criterion doctors will use to diagnose you. If you have at least four of the following symptoms, you may have lupus:
- Butterfly-shaped rash
- Raised red patches on your skin
- You’re sensitive to light
- Ulcers in your mouth or nose
- Arthritis in two or more joints, plus swelling or tenderness
- Inflammation in the lining of your heart or lungs
- Seizures or other nerve problems
- Too much protein in your urine
- Low blood cell counts
- Certain antibodies in your blood
- Results from a blood test called an ANA test that suggest you may have too many “antinuclear” antibodies
Although there is no cure for lupus, your doctor will be able to help you successfully manage the condition and improve your quality of life, however, through a combination of treatments.