several years and is characterized by the slow accumulation of immature white blood cells in the bone marrow and blood.
Some people may not be diagnosed with CML until they reach the accelerated phase or blast phase, when symptoms become more severe.
Accelerated Phase Symptoms
As the disease progresses, it may enter the accelerated phase, where symptoms become more severe. Symptoms of the accelerated phase may include increased fatigue and weakness, persistent fever, increased abdominal discomfort, and rapid weight loss. The accelerated phase is a critical period in the progression of CML, as it indicates that the disease is becoming more aggressive and may require more intensive treatment.
Blast Phase Symptoms
The blast phase is the most advanced stage of CML and is characterized by a rapid increase in immature white blood cells, called blasts. Symptoms of the blast phase may include severe fatigue and weakness, increased risk of infections, bleeding or bruising easily, and bone pain. The blast phase is a life-threatening stage of CML and requires immediate medical attention.
Seeing a Doctor
If you experience any symptoms of CML, it is important to see a doctor promptly for an accurate diagnosis. Your doctor may perform a physical exam, blood tests, and a bone marrow biopsy to confirm the diagnosis and determine the stage of the disease. Early detection and treatment of CML can significantly improve your outlook and quality of life.