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Home / Health Conditions / Tardive Dyskinesia / Tardive Dyskinesia & Parkinson’s Disease: What’s The Difference?

Tardive Dyskinesia & Parkinson’s Disease: What’s The Difference?

The crippling side effect of certain prescribed medications known as Tardive Dyskinesia still tackles up to 30 percent of patients who take antipsychotic drugs long-term. Most identified from uncontrollable muscle movements, much like Parkinson’s Disease, the disorder causes involuntary jerks, tics, and joint stiffness.

However, it’s important not to confuse the two, and here’s why:

Tardive Dyskinesia Is Not To Be Mistaken for Parkinson’s Disease

Although tardive dyskinesia is often mistaken for symptoms of Parkinson's disease, the two conditions are similar, but there are important differences. According to the Northwest Parkinson’s Foundation, Tardive Dyskinesia and Parkinson’s Disease are both categorized as movement disorders and are linked to dopamine, which carries signals from the brain throughout the body and regulates bodily functions. Both can result as a side effect of certain medications, however, the similarities stop there. For one, the symptoms of Parkinson's and tardive dyskinesia have opposite effects on patients' motor skills.

Certain Medications Play A Big Role in Tardive Dyskinesia

The most recent and probably lesser known as a direct link to tardive dyskinesia besides the most prevalent neuroleptics, butyrophenones, Diphenylbutylpiperdines, Indolones, Phenothiazines, Thioxanthenes medications, is the use of the drug Reglan. Used as a short-term treatment for heartburn and acid reflux, Reglan (metoclopramide) is a prescribed medication that increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines. However, if taken over 12 weeks, it can cause tardive dyskinesia.

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One of the factors that prevent patients from recognizing Reglan side effects is their similarity to other neurological health problems like Parkinson’s. In fact, Reglan side effects include uncontrollable muscle movements of your lips, tongue, eyes, face, arms, or legs. The longer you take Reglan, the more likely you are to develop serious movement disorder. The risk of this side effect is higher in women, diabetics, and older adults.

Parkinson’s Is About Genetics and Environmental Factors and More

According to the Parkinson’s Foundation, scientists haven’t determined the exact cause of Parkinson’s disease but believe a combination of genetic and environmental factors are involved. People with Parkinson’s experience difficulties with movement including slowness of movement and rigidity. Furthermore, the movements associated with tardive dyskinesia are more fluid and less jerky than the spasms and stiffness experienced by those with Parkinson’s.

Symptoms of Parkinson's include muscular rigidity, tremors and shaking, impaired speech and loss of movement ability. Tardive dyskinesia causes tongue-thrusting, fluttering fingers, restless legs, toe-tapping, and facial tics, including lip-smacking and pursing, grimacing and rapid blinking.

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Both Conditions Are Incurable But Can Be Managed Through Medication

Those who have taken Reglan and think they have Parkinson's disease could also benefit from speaking with a doctor. According to the Tardive Dyskinesia Center, Reglan has been linked to symptoms of Parkinson's disease. Some patients who had Parkinson's prior to taking Reglan say they noticed greater difficulty moving after taking the drug. Seek out more information by finding a specialist you can trust on our Find A Doctor page on BlackDoctor.org.


More Information

The Parkinson’s Foundation has more on living well with Parkinson’s Disease.

 

 

Tia Muhammad, BS, is an award-winning freelance content & media creative, copywriter, blogger, digital designer, and marketing consultant. She owns the boutique content and digital media company, jackieGLDN|studio.

By Tia Muhammad | Published August 24, 2023

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