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Home / Health Conditions / NMOSD / This Disease Acts and Feels Like MS, How Do You Tell The Difference?

This Disease Acts and Feels Like MS, How Do You Tell The Difference?

neuromyelitis optica

Symptoms can be tricky because the minute we think we’ve gotten to the route of what’s causing them, we may be shocked to learn that something else is the cause. For example, all your symptoms may point to a diagnosis of multiple sclerosis (MS), when you actually have neuromyelitis optica (NMO). If you’re guilty of using Google as a method of diagnosing yourself when something is off, then you’ve probably been down this road before. Some diseases and illnesses have similar symptoms, that’s why it’s best to see a doctor when you are experiencing symptoms in order to get an accurate diagnosis.

What is neuromyelitis optica?

NMO is a rare autoimmune disease that affects the central nervous system. It’s also called Devic’s disease. NMO specifically affects the myelin, which is the insulation around the nerves. NMO mainly affects the spinal cord and the optic nerves—the nerves that carry signals from the eyes to the brain. As a result, the disease can cause paralysis and blindness.

NMO most often strikes between the ages of 30 and 39. But it can also start during childhood. It can also affect adults who are in their 40s. It’s especially common in young women, but men can develop it, too.

Because NMO and MS have similar symptoms, experts once believed that it was a type of multiple sclerosis, so it makes sense if you previously believed you had MS. Today, NMO is grouped with related syndromes under the unifying term “neuromyelitis optica spectrum disorder (NMOSD).

We know how they’re similar, but all this talk about MS vs. NMO probably has you wondering how the two differ. For starters, the symptoms are usually more severe in NMO. For example, vision problems with multiple sclerosis usually affect 1 eye at a time, while NMO may affect both eyes at the same time.

What are the symptoms of neuromyelitis optica?

These are possible symptoms of NMO:

  • Pain in the eyes
  • Loss of vision
  • Weakness or numbness in the arms and legs
  • Paralysis of the arms and legs
  • Difficulty controlling the bladder or bowels
  • Uncontrollable vomiting and hiccups

There are 2 types of NMO:

  • Relapsing form, which has periodic flare-ups, with some recovery in between. This is the more common kind. Women are far more likely to have this form than men.
  • Monophasic form, which involves a single attack that lasts a month or two. Men and women get this type equally.

Unlike MS, NMO doesn’t have a progressive course. The symptoms of NMO are solely due to attacks.

RELATED: Getting the Diagnosis Right With Multiple Sclerosis

What causes NMO?

With NMO, your immune system attacks a substance in your body called myelin—the insulation around your nerves. Specifically, the myelin cells in the spinal cord and optic nerves are attacked. Usually, people with NMO have flare-ups of the disease that may strike months or years apart. Between these flare-ups, you may experience some recovery.

person
Photo via Cedars-Sinai

 

How is neuromyelitis optica diagnosed?

Confused about which disease you have? If you suspect you might have either of these nerve conditions, see your doctor for a proper diagnosis.

Your healthcare provider may do a variety of tests if they suspect NMO, such as:

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